Peptan / Joint & Bone Health


The efficacy of collagen peptides in supporting joint health is supported by an extensive body of scientific studies


As people enjoy active lifestyles and wish to maintain mobility into their senior years, they are becoming more aware of joint and bone health starting from an early age. And it is not only those with advancing age who feel it. Even the ‘weekend warriors’ among us (who exercise once or twice a week) can often feel the strain on our joints – let alone the professional athletes! Collagen is the key structural component of cartilage tissue and maintaining its integrity is essential to maintain healthy and flexible joints.

Bones are a dynamic tissue that constantly go through a well-balanced breakdown and renewal process. This ensures them to stay healthy and to avoid fractures throughout our lives. 90% of our organic bone mass is collagen. Collagen provides the organic framework in bones on which minerals are deposited and also contribute to bone flexibility and strength. With age or certain lifestyle choices, bones can deteriorate.

Old people performing lunges

Peptan has been demonstrated in science to promote joint and bone health. Peptan IIm, Hydrolyzed Collagen Type II Matrix has been developed to boost joint health at a low daily dosage


Discover the science behind Peptan.

Peptan IIm for joint health

Extracted from natural sources, Peptan IIm is a unique hydrolyzed cartilage matrix that contains bioactive Type II collagen peptides and glycosaminoglycans - chondroitin sulfate and hyaluronic acid. The components it contains are effective to protect healthy cartilage from degeneration (1).

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Peptan IIm's science

In an in vivo study (1), Peptan IIm has been demonstrated to be effective at a low dose corresponding to 0.75g/day in humans. In models of post-traumatic osteoarthritis in both normal-weight or obese animals, Peptan IIm:

Protects the cartilage from degeneration and promotes lubrication

Shows anti-inflammatory action in the knee joint (local inflammation)

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Peptan maintains healthy joint

In a clinical trial (2), 94 women aged 40-70 with knee joint problems received 8g of Peptan or placebo daily for a period of 6 months.

Peptan supplementation resulted in a statistically significant reduction in the WOMAC score by 22% linked to a 32% decrease in joint pain and 44% improvement of stiffness.

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Peptan supports bone health

In a recently published study (3) Peptan has been shown to stimulate the activity of bone-forming cells and at the same time to inhibit the function of bone-resorbing cells. This result is in line with previous studies performed with Peptan (4)(5).

Graphical representation of the bone mechanism
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There is more science and knowledge behind Peptan and Peptan IIm