How consumers needs are fueling demand for science-based joint health supplements

Consumers of all ages are enjoying active lifestyles. Many of them engage in physical activities that put their bodies, especially their joints, under pressure. There is an expanding base of consumers engaging in sports and fitness who are looking to maintain joint health. Joint stiffness and discomfort are often associated with aging and most likely affect the joints that have been continually stressed throughout the years. These include the knees, hips, fingers, and lower spine region. Combined with an aging population and a reluctance towards taking medication, this opens possibilities for scientifically sound joint health supplements.

What consumers expect from joint health supplements

Consumers today look for effective and proactive support of their physique in order to maintain an active lifestyle. They also seek proven solutions that can effectively:

  • Relieve joint discomfort and improve joint function;
  • Protect cartilage and prevent future problems;
  • Offer a convenient and attractive delivery format.

Consumers understand that healthy cartilage is the key to healthy joints. Their awareness of the role of collagen as the main tissue component is also increasing.

The ideal joint ingredient should stimulate regeneration of cartilage matrix as well as help counteract inflammation to protect joints and alleviate symptoms.


The role of healthy cartilage

Cartilage is essentially made up of a gel-like substance called the ‘matrix’, which gives it its form and function.

Matrix consists predominantly of collagen (II) fibers (approx. 75%) and GAG’s, like aggrecan (a large Chondroitin Sulfate proteoglycan), chondroitin sulfate and hyaluronic acid.

Aging or excessive stress or load on joints can cause joint health issues such as joint discomfort, stiffness and locking.


What is Collagen Type II?

Collagen type II originates from cartilage. Collagen type II in its purest form is very similar to a collagen type I molecule – the difference being that the triple helix of type II collagen is composed of 3 alpha-1 chains. Collagen type II is found in a natural matrix with Glycosaminoglycans (GAG’s): Chondroitin sulfate and Hyaluronic acid. 


Introducing Peptan IIm, hydrolyzed collagen type II matrix

Peptan IIm's joint health benefits backed by science

Extracted from natural sources, Peptan IIm is a unique hydrolyzed cartilage matrix that contains hydrolyzed collagen Type II in the form of bioactive peptides and glycosaminoglycans - chondroitin sulfate and hyaluronic acid. It provides all the essential building blocks for maintaining and regenerating healthy cartilage. In a recent in vivo study1, Peptan IIm has been demonstrated to be effective at a low dose: 

  • In post-traumatic osteoarthritis

    • Protects the cartilage from degeneration and promotes lubrication
    • Anti-inflammatory action in the knee joint (local inflammation) 

  • In post-traumatic osteoarthritis of obesity 

    • Protects the cartilage from degeneration and promotes lubrication
    • Anti-inflammatory action in the knee joint (local inflammation)

  • In obesity 

    • Helps to reduce systemic inflammation

Peptan IIm has a high absorption rate, indicated by high levels of hydroxyproline after one hour of feeding of the animal model in the same study.


3 Joint Health Dimensions


Reference

1. Soniwala, S. et al., 2018, Oral Hydrolyzed Type 2 Collagen Protects Against the OA of Obesity and Mitigates Obese Gut Microbiome Dysbiosis. Poster presentation at ORS 2018 and OARSI 2018