Demonstrated in scientific studies

To ensure bioactivity, it is essential to have exceptional bioavailability of collagen in the target tissues. Peptan has been shown to have high digestibility and excellent absorption. More than 90% of Peptan is digested and available as small peptides in the blood stream within one hour. From the blood the peptides (containing hydroxyproline, a unique amino acid) are transported into the target tissues, e.g. skin, bones and cartilage, where they act as building blocks for the local cells and help boost the production of new collagen fibers. 

Excellent digestibility

In a model1 imitating digestion in the human gastro-intestinal tract, different types of Peptan were tested for their digestibility. 

  • Over 90% of Peptan was digested into peptides with a molecular weight below 2000 Dalton, a size that allows easy absorption by the intestine. Peptan P (porcine), B (bovine) and F (fish) performed equally well
  • Results confirm similar studies, and suggests that Peptan is easily and completely digested after intake

Excellent absorption

In an in vivo study2, the appearance of free and peptide-bound hydroxyproline was measured in the blood at different time points over 24h after ingestion of Peptan 

  • Peptan is quickly absorbed with an absorption peak at 0.5 to 1 hour after ingestion of the product.
  • Results confirm that Peptan is very efficiently absorbed into the blood

These results are in line with reports from other studies showing that collagen peptides are absorped in high concentration into the blood3,4.

High bioavailability of collagen peptides

Several in vivo studies5 demonstrate, by the use of labeled collagen peptides that when present in the blood, the peptides will reach the connective tissues.

  • The labels were found in different tissues, such as cartilage, bone, muscle and skin already 1 to 2 hours after ingestion. In skin, labeling was still detectable at a high level after 14 days.
  • Studies confirm that collagen peptides reach the target tissues efficiently, where their action is beneficial.