In virtually every country of the world, the population is aging, while health and wellness expectations are rising. The opportunities for manufacturers of food and dietary concepts are immense. Peptan collagen peptides are the natural choice for manufacturers looking to boost the nutritional profile of their products and develop solutions with proven health benefits to improve the quality of life of the aging consumers.
Today’s active agers look for functional foods that taste great, convenient and easy to consume. Peptan embraces this demand, its exceptional organoleptic and functional properties make it easy to integrate into senior diet.
Peptan is a bioactive protein supporting healthy aging
As one of the most extensively researched collagen peptides on the market, the efficacy of Peptan in promoting mobility is supported by an impressive body of scientific evidence. Peptan is unique as it simultaneously supports all the connective tissues by stimulating local cells in the target tissues to produce more collagen and other key matrix components. A wide range of studies has demonstrated Peptan’s ability to promote healthy joints and strong bones. Collagen peptides also support lean muscle mass and strength.
Wear and tear on joints can cause stiffness and discomfort in older adults. Collagen is fast becoming the preferred active ingredient for joint health supplements and the efficacy of Peptan for improving joint function and reducing discomfort is backed by scientific studies including in vitro, in vivo and clinical trials.
In a randomized, placebo-controlled, double-blind clinical trial1, 94 women aged 40-70 with knee joint problems (osteoarthritis classification: 0-III) received 8g of Peptan or placebo daily for a period of 6 months.
The same study also sought to discover whether Peptan could improve knee joint function in the same group of women.
In an in vitro study2, primary cartilage cells (chondrocytes) were cultured in the presence of different concentrations of Peptan for 8 days to demonstrate Peptan’s ability to induce the production of the key cartilage components, aggrecan and type 2 collagen, which make up the joint tissue.
A new in vivo study3 confirms Peptan's role in supporting joint health, providing scientific documentation of the mechanisms behind cartilage regeneration and joint inflammation reduction. Peptan is:
Maintaining strong bones reduces the risk of fractures later in life. Collagen makes up the structural framework on which minerals are deposited. When taken as a supplement, collagen peptides can support healthy and strong bones, as shown in multiple in vitro, in vivo and clinical trials4-7. Peptan can stimulate the endogenous production of collagen in bone tissue, triggering osteoblasts (bone formation cells) and increasing bone size and firmness.
Peptan can ideally be combined with calcium and vitamin D to offer optimal bone health benefits.
In an in vivo study4 an established model that mimics the loss of bone mass (osteopenia) in postmenopausal women (Ovx) was used to investigate the effect of Peptan supplementation– the experimental group (Ovx + Peptan) received a daily dose of Peptan for 3 months in addition to a normal diet (with adequate level of calcium, protein and Vitamin D). The Ovx and Control group received a normal diet only.
The same study as above also investigated the microarchitecture and strength of bones and demonstrate the following:
The mechanisms behind Peptan’s bone health benefits are well known. As an example, Peptan was compared to a control protein in below in the vitro study5, referred to below, primary bone cells were cultured in the presence of Peptan for 2 weeks.
Sarcopenia is the age-related loss of muscle mass and function. Exercise and adequate intake of easily digestible protein is vital to counteracting the condition's effects. The recommended protein intake for healthy adults is 0.8g/kg body weight per day8. However, older people can benefit from a higher intake which is often difficult as their diets often lack protein. As a bioactive protein, Peptan can help maintain lean body mass in older adults.
In a double-blind, crossover trial9, nitrogen balance was compared in a group of elderly women aged 65 - 85 who consumed a diet supplemented with either whey protein or collagen peptides.